ModuleMedications

Study module: cryptogenic stroke + PFO concepts (workup and prevention)

Study module on embolic stroke of undetermined source/cryptogenic stroke: structured workup concepts (including rhythm monitoring) and when PFO closure may be considered (conceptual)

ClinicianClinicianAdvanced25 minClinical (pro)

Educational only

Educational only — ESUS/PFO management requires guideline criteria and specialist evaluation.

Get help now

New or worsening neurologic deficit is an emergency: activate local stroke alert/emergency response immediately and document last known well time. Etiology workup should not delay acute care.

What you'll learn

  • Define cryptogenic/ESUS conceptually
  • List common evaluation components (high-level)
  • Explain why prolonged rhythm monitoring matters
  • Describe PFO closure consideration themes (no thresholds)

Definitions (concept)

  • Cryptogenic
  • ESUS concept

Workup framework

  • Vascular imaging
  • Echo/structural evaluation
  • Rhythm monitoring
  • Labs as appropriate

Prevention strategy categories

  • Risk factor control
  • Antithrombotics per etiology
  • PFO closure consideration in selected patients

Exam pearls

  • Don’t assume ‘unknown’ means ‘no cause’
  • Document what’s ruled out

Practice check

Check your understanding

A few untimed questions. Pick an answer to see instant feedback, then continue to the next lesson.

0 of 2 answered

Question 1

1. Prolonged rhythm monitoring can detect paroxysmal AFib in some cryptogenic strokes.

Question 2

2. PFO closure considerations are typically relevant in…

References

  1. AHA/ASA 2021 Secondary Prevention Guideline logo